A PiLot ClinicaL TrIal of ParicAlcitol for ChroNiC PancrEatitis
The purpose of this pilot study to examine the feasibility and acceptability of paricalcitol in adults with Chronic Pancreatitis (CP).
| Condition(s) | Chronic Pancreatitis |
|---|---|
| Status | Recruiting |
| Phase | EARLY_Phase 1 |
| Study type | Interventional |
| Summary | The purpose of this pilot study to examine the feasibility and acceptability of paricalcitol in adults with Chronic Pancreatitis (CP). |
| Who can participate | Inclusion Criteria: * Provision of signed and dated informed consent form * Stated willingness to comply with all study procedures and availability for the duration of the study * Male or female, aged 18-75 at time of enrollment * Diagnosis of Chronic Pancreatitis episode is not attributable to gallstones (i.e. suspected or definite biliary etiology), medications, trauma or autoimmune pancreatitis. * Ability to take oral medication and be willing to adhere to the dosing regimen * Normal Calcium levels- 8.5 to 10.2 mg/dL * Normal Phosphate levels- 2.8 to 4.5 mg/dL * Normal Parathyroid hormone levels- 10 to 65 pg/mL * For females of reproductive potential: use of highly effective contraception for at least 1 month prior to screening and agreement to use such a method during study participati |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Lead sponsor | Cedars-Sinai Medical Center |
| Locations | Los Angeles, California, United States |
| Start date | 2023-06-01 |
| NCT ID | NCT05664880 |
| Official listing | https://clinicaltrials.gov/study/NCT05664880 |