A Pilot Study of the Effect of the Combination of Inhaled Nitric Oxide and Prone Position
Investigating the Impact of Combined Inhaled Nitric Oxide and Prone Positioning on the Efficacy in ARDS Patients
| Condition(s) | ARDS |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | Investigating the Impact of Combined Inhaled Nitric Oxide and Prone Positioning on the Efficacy in ARDS Patients |
| Who can participate | Inclusion Criteria: 1. Age 18-80 years; 2. Patients with moderate to severe ARDS on mechanical ventilation Exclusion Criteria: 1. Patients with severe asthma or acute exacerbation of chronic obstructive pulmonary disease (COPD), lung tumors, post-lung resection, and post-lung transplantation. 2. Patients with hemodynamic instability requiring vasopressor support: dopamine or dobutamine \>15 µg/kg/min, norepinephrine \>0.3 µg/kg/min. 3. Cardiogenic pulmonary edema. 4. Patients with severe facial deformities, facial trauma, or severe thoracoabdominal trauma that precludes prone positioning ventilation. 5. Mid to late pregnancy. 6. Patients with a history of malignancy or other irreversible diseases/conditions, including those in the terminal stage. 7. Patients expected to be discharged soon |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Lead sponsor | Northern Jiangsu People's Hospital |
| Locations | Yangzhou, Jiangsu, China |
| Start date | 2024-01-01 |
| NCT ID | NCT06741137 |
| Official listing | https://clinicaltrials.gov/study/NCT06741137 |