A Real-world Study of the Efficacy and Safety of ICIs as First-line Therapy for Advanced M
In this study, we collected the data of immunohistochemistry, gene detection, image, OS, PFS, Orr, and so on. Secondly, the database of immunotherapy for malignant tumor was established, and the predictive model was constructed to verify and establish the rationality and validity of the biomarkers and predictive system
| Condition(s) | Malignant Tumor, Immunotherapy, Artificial Intelligence |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | In this study, we collected the data of immunohistochemistry, gene detection, image, OS, PFS, Orr, and so on. Secondly, the database of immunotherapy for malignant tumor was established, and the predictive model was constructed to verify and establish the rationality and validity of the biomarkers and predictive system of immunotherapy |
| Who can participate | Inclusion Criteria: 1. Informed consent has been signed and, in the judgment of the investigator, the patient is able to comply with the study protocol and sign a written informed consent. 2. the advanced malignant tumors (solid tumors of the non-small-cell lung carcinoma, stomach, breast, urinary system, etc.) were diagnosed by histopathology. 3. the stage IV according to the eighth edition of IASLC. 4. PS 0-2, the expected survival \> 3 months. 5. the age of 18-75 years. 6. no contraindication to treatment with immune checkpoint inhibitors. Exclusion Criteria: 1. the patients' compliance was poor, which violated the rules of the trial; 2. the patients with severe dysfunction of vital organs (heart, liver and kidney) ; 3. the patients with other malignant tumors; 4. the researchers consid |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Lead sponsor | Xinqiao Hospital of Chongqing |
| Locations | Chongqing, Chongqing Municipality, China |
| Start date | 2023-08-10 |
| NCT ID | NCT05862259 |
| Official listing | https://clinicaltrials.gov/study/NCT05862259 |