A Study of Females With CF Throughout Pregnancy and Post-partum, and Follow up of Their Of
In this study, investigators aim to study in detail the physical (including nutritional and pulmonary) and mental health of females with cystic fibrosis (CF) planning a pregnancy, during pregnancy, and in the early parenthood period. Additionally the health of offspring in infancy and early life will be studied to unde
| Condition(s) | Cystic Fibrosis (CF), Pregnancy, Infant, Newborn, Exposure During Pregnancy |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | In this study, investigators aim to study in detail the physical (including nutritional and pulmonary) and mental health of females with cystic fibrosis (CF) planning a pregnancy, during pregnancy, and in the early parenthood period. Additionally the health of offspring in infancy and early life will be studied to understand if further screening investigations or clinical care models should be part of clinical guidelines |
| Who can participate | Inclusion Criteria: 'Mama' sub-study: * Written informed consent obtained from participant. * Under the care of Royal Brompton Hospital CF Reproductive and Maternal Health Service * Age 16 years or above at time of recruitment * Confirmed diagnosis of CF * Planning a pregnancy or pregnant at time of recruitment. * Ability to adhere to the required visits and investigations. 'Mini' sub-study: * Written informed consent obtained from participant's legal guardian. * Infants who have one biological parent with a confirmed diagnosis of CF under care of Royal Brompton Hospital Adult CF Service * Less than 12 months of age at first visit. * Ability to adhere to the required visits and investigations. 'Midi' sub-study: * Written informed consent obtained from participant's legal guardian. * Childr |
| Sex | All |
| Lead sponsor | Royal Brompton & Harefield NHS Foundation Trust |
| Locations | London, United Kingdom |
| Start date | 2025-06-12 |
| NCT ID | NCT06797206 |
| Official listing | https://clinicaltrials.gov/study/NCT06797206 |