A Study to Evaluate Novel KarX and KarT Prototypes Versus the KarXT and KarX-EC Reference
The purpose of this study is to evaluate novel KarX and KarT prototypes versus the KarXT and KarX-EC reference following single doses, and to explore the effect of food after multiple doses of selected prototypes in healthy adult participants.
| Condition(s) | Healthy Volunteers |
|---|---|
| Status | Recruiting |
| Phase | Phase 1 |
| Study type | Interventional |
| Summary | The purpose of this study is to evaluate novel KarX and KarT prototypes versus the KarXT and KarX-EC reference following single doses, and to explore the effect of food after multiple doses of selected prototypes in healthy adult participants. |
| Who can participate | Inclusion Criteria: * BMI between 18.0 kg/m2 to 32.0 kg/m2, inclusive, at screening. * Other protocol-defined Inclusion/Exclusion criteria apply. |
| Ages | 18 Years to 55 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | Bristol-Myers Squibb |
| Locations | Nottingham, Nottinghamshire, United Kingdom |
| Start date | 2025-06-27 |
| NCT ID | NCT07063342 |
| Official listing | https://clinicaltrials.gov/study/NCT07063342 |