Application Value of Whole-procedure Optimization for Catheter Ablation of Atrial Fibrilla
The success rate of single-procedure atrial arrhythmia-free survival particularly ranged from 40% to 66% in persistent AF ablation. However, The surgical Cox maze III procedure has been established to be an effective curative strategy for AF with an AF-free survival rate of more than 95%. The main reason is the difficu
| Condition(s) | Atrial Fibrillation |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | The success rate of single-procedure atrial arrhythmia-free survival particularly ranged from 40% to 66% in persistent AF ablation. However, The surgical Cox maze III procedure has been established to be an effective curative strategy for AF with an AF-free survival rate of more than 95%. The main reason is the difficulty of creating continuous, transmural, and durable lesions by catheter ablation, especially when the procedure is performed on some complex anatomical structures in which epicardial muscular bundles may serve as components of the reentrant circuits. The durability of the conduction block is a crucial factor for long-term effective AF ablation since previous studies reported that the reconnected Pulmonary veins contributed to the atrial tachycardia recurrence after persistent |
| Who can participate | Inclusion Criteria: * Radiofrequency catheter ablation for the first time * AF rhythm recorded by ECG Exclusion Criteria: * Thrombosis in left atrium * Left ventricular ejection fraction of \< 35% * Abnormal thyroid function * Previous history of AF radiofrequency ablation and CABG * Left atrium diameter of \> 65 mm or the volume of \> 200 ml |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Lead sponsor | Henan Provincial People's Hospital |
| Locations | Zhengzhou, Henan, China |
| Start date | 2023-12-26 |
| NCT ID | NCT06145906 |
| Official listing | https://clinicaltrials.gov/study/NCT06145906 |