Auditory Functions in Patients With Multiple Sclerosis
The study will analyze the auditory functions of patients with Multiple Sclerosis using auditory tests like pure tone auditory test, speech perception test, Auditory Brain Response (ABR) and Distortion Product Otoacustic Emission (DPOAE). CSF will be collected by lumbar puncture and analyzed looking for inflammatory ma
| Condition(s) | Multiple Sclerosis, Hearing Disorders |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | The study will analyze the auditory functions of patients with Multiple Sclerosis using auditory tests like pure tone auditory test, speech perception test, Auditory Brain Response (ABR) and Distortion Product Otoacustic Emission (DPOAE). CSF will be collected by lumbar puncture and analyzed looking for inflammatory markers. The results of DPOAE and CSF will be correlated to identify statistically significant correlation. |
| Who can participate | Inclusion Criteria * age \>18 and \<50, * no history of hearing loss, * no psychiatric condition * no familial history of otosclerosis/deafness/genetic hearing loss * patients with PD and/or MS. Exclusion Criteria * Conductive hearing loss * stroke \< 2 years * cardiovascular disease non under control * diabetes * hypotensive disorders * alcohol abuse * recreational drug consumption * epilepsy |
| Ages | 20 Years to 40 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | University of Catania |
| Locations | Catania, Sicily, Italy |
| Start date | 2026-05-11 |
| NCT ID | NCT06164483 |
| Official listing | https://clinicaltrials.gov/study/NCT06164483 |