Australian Genomics Of Chronic Allograft Dysfunction Study
The goal of the Australian Genomics of Chronic Allograft Dysfunction (AUSCAD) study is a single centre (Westmead Hospital), prospective, observational study, which enrols patients at time of kidney (or kidney-transplant) transplant and tracks the post transplant course. The AUSCAD study aims to generate new knowledge a
| Condition(s) | Kidney Transplant Rejection, Kidney Transplant; Complications |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | The goal of the Australian Genomics of Chronic Allograft Dysfunction (AUSCAD) study is a single centre (Westmead Hospital), prospective, observational study, which enrols patients at time of kidney (or kidney-transplant) transplant and tracks the post transplant course. The AUSCAD study aims to generate new knowledge and improve outcomes following kidney transplantation. The primary aim is to determine whether important outcomes (including chronic rejection and graft loss) are correlated with patterns of allograft reactivity, gene expression and susceptibility profiles. |
| Who can participate | Inclusion Criteria: * Living or deceased donor kidney transplant candidate. * Biological sex: any * Ages: 18-75 years. * Subject must be able to understand and provide informed consent. * Deceased donor individuals where Research Consent has been obtained from the person consenting to organ donation at the time of organ retrieval. * Identifiable living donors who have received informed consent and have consented to participate in the project. Exclusion Criteria: * Presensitization in living donor recipients prior to transplantation, as determined by site-specific standards, OR positive cross match according to site specific technique in cadaveric donor recipients. * Recipients of multiple organ transplants, with the exception of kidney/pancreas transplants. * Inability or unwillingness of |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Lead sponsor | Western Sydney Local Health District |
| Locations | Westmead, New South Wales, Australia; Westmead, New South Wales, Australia |
| Start date | 2012-04-26 |
| NCT ID | NCT06314230 |
| Official listing | https://clinicaltrials.gov/study/NCT06314230 |