Balancing Kinematically Aligned Total Knee Replacements During Total Primary Knee Arthropl
Total Knee Replacement (TKR) is an operation to help with the pain and decreased function that happens with end stage arthritis of the knee. This operation has been shown to be very successful at relieving pain and improving patient mobility; however, some studies have shown that up to 20% of TKR recipients are not hap
| Condition(s) | Osteo Arthritis Knee |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | Total Knee Replacement (TKR) is an operation to help with the pain and decreased function that happens with end stage arthritis of the knee. This operation has been shown to be very successful at relieving pain and improving patient mobility; however, some studies have shown that up to 20% of TKR recipients are not happy with their knee replacement. All of the reasons why some patients are not pleased with the outcome of surgery are not known, but one of the possible causes is the way the implants are placed, or aligned, during surgery. Most TKRs are aligned in a fashion that the bones in the leg are completely straight after surgery. This is known as mechanically aligning a TKR. A different alignment method known as kinematic alignment respects the natural bow legged or knock kneed alignm |
| Who can participate | Inclusion Criteria: * Symptomatic arthritis of the knee indicating primary total knee arthroplasty * Between the ages of 21 and 80 inclusive * Patients willing and able to comply with follow-up requirements and self-evaluations * Ability to give informed consent * Varus alignment Exclusion Criteria: * Patients less than 21 years of age, or 81 years of age and older * Unable to provide consent * BMI \>45 * Pregnancy * Patients with inflammatory arthritis, posttraumatic osteoarthritis, post high tibial osteotomy, or arthritis due to sepsis will be excluded. * Active or prior infection * Medical condition precluding major surgery * Severe osteoporosis or osteopenia * Neuromuscular impairment * Significant co-morbidity affecting ability to ambulate * Valgus alignment |
| Ages | 21 Years to 80 Years |
| Sex | All |
| Lead sponsor | Nova Scotia Health Authority |
| Locations | Halifax, Nova Scotia, Canada |
| Start date | 2018-07-23 |
| NCT ID | NCT03286868 |
| Official listing | https://clinicaltrials.gov/study/NCT03286868 |