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Better Evidence and Translation for Calciphylaxis

This global platform study will evaluate multiple interventions, across several domains of therapeutic care, in adult patients with kidney failure and newly diagnosed calciphylaxis.

Condition(s)Calciphylaxis
StatusRecruiting
PhasePhase 3
Study typeInterventional
SummaryThis global platform study will evaluate multiple interventions, across several domains of therapeutic care, in adult patients with kidney failure and newly diagnosed calciphylaxis.
Who can participateInclusion Criteria: 1. Currently receiving haemodialysis, or peritoneal dialysis that can be converted to haemodialysis, with planned ongoing haemodialysis a minimum of three times per week for at least the duration of the protocolised calciphylaxis treatments within this trial 2. Have a new calciphylaxis ulcer present for less than 10 weeks 3. Age ≥ 18 years 4. Eligible for randomisation in at least one recruiting domain 5. The participant and treating physician are willing and able to perform trial procedures Exclusion Criteria: Nil
Ages18 Years
SexAll
Lead sponsorUniversity of Sydney
LocationsConcord, New South Wales, Australia; Kogarah, New South Wales, Australia; Liverpool, New South Wales, Australia; New Lambton Heights, New South Wales, Australia; Westmead, New South Wales, Australia; Birtinya, Queensland, Australia (+15 more sites)
Start date2021-08-26
NCT IDNCT05018221
Official listinghttps://clinicaltrials.gov/study/NCT05018221

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