Biofiller and Gingival Phenotype Thickening
The periodontal phenotype is defined as the combination of the gingival phenotype and the thickness of the buccal bone plate (bone morphotype). The gingival phenotype refers to the gingival thickness (GT) and the width of the keratinized tissue (KTW). A gingival thickness of ≤1 mm is classified as a thin phenotype, whe
| Condition(s) | Gingival Recession, Gingival Diseases, Gingival Inflammation |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The periodontal phenotype is defined as the combination of the gingival phenotype and the thickness of the buccal bone plate (bone morphotype). The gingival phenotype refers to the gingival thickness (GT) and the width of the keratinized tissue (KTW). A gingival thickness of ≤1 mm is classified as a thin phenotype, whereas a thickness \>1 mm is considered a thick phenotype. Thin gingival biotypes tend to show more pronounced responses to inflammation, restorations, trauma, and parafunctional habits. Various methods are used to assess gingival thickness, including transgingival probing (TP), ultrasonic measurements, cone-beam computed tomography (CBCT) scans, visual assessment, and colored biotype probes (CBP). Periodontal plastic procedures performed using autogenous grafts such as connect |
| Who can participate | Inclusion Criteria: * Age between 18 and 60 years * Systemically healthy individuals * Presence of thin gingival phenotype in the mandibular anterior region (canine to canine) * No medications that affect wound healing * No history of bleeding disorders * No known allergy to anti-inflammatory drugs * Not pregnant or breastfeeding * Willingness to participate and provide informed consent * Non-smoker Exclusion Criteria: * Systemic diseases (e.g., diabetes, hypertension, cancer, etc.) * Use of medications that may affect healing (e.g., corticosteroids, immunosuppressants) * History of radiotherapy or chemotherapy * Pregnancy or breastfeeding * Poor oral hygiene * Refusal to participate * Age under 18 years * Smoking * Presence of Class II or Class III orthodontic anomalies |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | Inonu University |
| Locations | Malatya, Turkey (Türkiye) |
| Start date | 2025-07-30 |
| NCT ID | NCT07104019 |
| Official listing | https://clinicaltrials.gov/study/NCT07104019 |