Bowel Function/QoL After Elective Sigmoidectomy vs. Conservative Management for Recurrent
The decision to perform a surgical intervention or not after recovery from repeated uncomplicated episodes of acute diverticulitis remains controversial and the literature shows different conflicting approaches based on low-quality evidence.The goal of this trial is to achieve a better understanding of the impact of su
| Condition(s) | Diverticulitis of Sigmoid |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | The decision to perform a surgical intervention or not after recovery from repeated uncomplicated episodes of acute diverticulitis remains controversial and the literature shows different conflicting approaches based on low-quality evidence.The goal of this trial is to achieve a better understanding of the impact of surgery on bowel function and QoL in patients with recurrent uncomplicated sigmoid diverticulitis in order to develop treatment guidelines. |
| Who can participate | Inclusion Criteria: * Patients with recurrent uncomplicated diverticulitis and surgical indication for sigmoid resection * Patients with recurrent uncomplicated diverticulitis and non-surgical indication for conservative management * Confirmation of at least one episode of acute uncomplicated diverticulitis in computed tomography Exclusion Criteria: * Patients aged under 18. * Patients unable to understand an informed consent. * Patients with chronic pain disorder. * Patients with sigmoid fistulas * Emergency operations. * Pregnant women or lactation. * Patients with other severe gastrointestinal diseases, such as inflammatory bowel diseases (IBD), carcinoma or immunologic disorders. * Patients unable to perform surgery or high-risk patients according to the American Society of Anesthesiol |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | University Hospital, Basel, Switzerland |
| Locations | Basel, Switzerland |
| Start date | 2019-07-08 |
| NCT ID | NCT03994978 |
| Official listing | https://clinicaltrials.gov/study/NCT03994978 |