Brain PERfusion Evaluation by Contrast-Enhanced UltraSound
The objective of the study is to assess brain tissue perfusion by contrast-enhanced ultrasound perfusion imaging (PerCEUS) in acute brain injuries. More precisely, it aims : * to evaluate the heterogeneity of brain perfusion and thus diagnose brain tissue hypoperfusion with contrast-enhanced ultrasound. * to correlate
| Condition(s) | Cerebral Hemorrhage, Subarachnoid Hemorrhage, Ischemic Stroke, Cerebrovascular Circulation, Perfusion |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | The objective of the study is to assess brain tissue perfusion by contrast-enhanced ultrasound perfusion imaging (PerCEUS) in acute brain injuries. More precisely, it aims : * to evaluate the heterogeneity of brain perfusion and thus diagnose brain tissue hypoperfusion with contrast-enhanced ultrasound. * to correlate contrast-enhanced ultrasound with perfusion measurements by usual multimodal monitoring. |
| Who can participate | Inclusion Criteria: * Age ≥18 * Intensive care unit admission for acute brain injury * Proven acute brain injury by CT and/or MRI * Requiring a contrast ultrasound imaging * Informed consent of patient or relative Exclusion Criteria: * Pregnancy * Not sufficient temporal window * Contraindications to Sonovue ® : acute coronary syndromes, severe ischemic heart disease (requiring revascularization), pulmonary arterial hypertension \> 90 mmHg, right-left shunt, ARDS, dobutamine's use, known allergy or adverse reaction to Sonovue® * Patient on State Medical Assistance |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | Assistance Publique - Hôpitaux de Paris |
| Locations | Paris, France |
| Start date | 2023-07-21 |
| NCT ID | NCT05893407 |
| Official listing | https://clinicaltrials.gov/study/NCT05893407 |