Breathing Patterns in Infants Before and After Extubation
The primary objective of this study is to compare work of breathing indices before and after extubation in intubated premature infants admitted to the Christiana Care Neonatal Intensive Care Unit. The secondary objective is to compare the ability of work of breathing indices to predict extubation failure to routine spo
| Condition(s) | Respiratory Distress Syndrome (RDS), PreTerm Neonate |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | The primary objective of this study is to compare work of breathing indices before and after extubation in intubated premature infants admitted to the Christiana Care Neonatal Intensive Care Unit. The secondary objective is to compare the ability of work of breathing indices to predict extubation failure to routine spontaneous breathing tests (SBTs) in intubated premature infants admitted to the ChristianaCare NICU. |
| Who can participate | Inclusion Criteria: * premature infants (born at ≤32 weeks gestation) who are intubated. * medical team is evaluating the baby for extubation readiness Exclusion Criteria: * Infants with skeletal, neuromuscular, or abdominal surgical disorders that affect the accuracy of RIP measurements will be excluded. |
| Ages | 0 Days to 6 Months |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | Christiana Care Health Services |
| Locations | Newark, Delaware, United States |
| Start date | 2025-04-14 |
| NCT ID | NCT07542301 |
| Official listing | https://clinicaltrials.gov/study/NCT07542301 |