Chitosan Phonophresis on Cervical IN Smartphone Addicted Users
A phonophoresis-based drug delivery system is a synchronous approach to improve local drug penetration in neuromuscular diseases associated with neuronal damage, excruciating pain, and local inflammation. Chitosan, a semi-synthetic material, is obtained by partial deacetylation of chitin amines, resulting in copolymers
| Condition(s) | Cervical Pain |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | A phonophoresis-based drug delivery system is a synchronous approach to improve local drug penetration in neuromuscular diseases associated with neuronal damage, excruciating pain, and local inflammation. Chitosan, a semi-synthetic material, is obtained by partial deacetylation of chitin amines, resulting in copolymers of N-acetylglucosamine and N-glucosamine. Its use has been explored in various biomaterial and medical applications. Chitosan has emerged as a cost-effective, biocompatible, and biodegradable material with many desirable biological properties, improvement of homeostasis and antiviral potential. Chitosan was found to suppress pro-inflammatory cytokines and decreased peripheral nerve edema, the polycationic nature of chitosan allows it to absorb protons, which reduces inflamma |
| Who can participate | Inclusion Criteria: * Their age will be ranged from 16-18 years * body mass index will be 26.58 kg/m2. * used a smart phone for more than 1 year for at least 2 hours per day * complaining of neck pain after using a smart phone, addiction to smart phone in accordance with the smart phone addiction scale (SAS) Exclusion Criteria: * any previous head and neck injuries or surgeries * any congenital abnormalities or symptomatic deformity in either the cervical or the lumbar spine * any uncorrected visual or auditory problems, dizziness, vertigo and headache * any systematic diseases, any addiction to alcohol, any additive drugs and sedatives within 48 hours previous to tests * body mass index of subjects over25 kg/m2. |
| Ages | 16 Years to 18 Years |
| Sex | All |
| Lead sponsor | October 6 University |
| Locations | Al Jīzah, Select State, Egypt |
| Start date | 2024-07-01 |
| NCT ID | NCT06491992 |
| Official listing | https://clinicaltrials.gov/study/NCT06491992 |