Combined Exercise and Nutrition Intervention for Sarcopenia
This study aims to demonstrate the effect of combined exercise-nutrition intervention in old adults with sarcopenia. This study will be conducted with prospectively randomized controlled trial comparing outcome of combined exercise-nutrition intervention with conventional medical care. Handgrip strength, gait speed, kn
| Condition(s) | Sarcopenia |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | This study aims to demonstrate the effect of combined exercise-nutrition intervention in old adults with sarcopenia. This study will be conducted with prospectively randomized controlled trial comparing outcome of combined exercise-nutrition intervention with conventional medical care. Handgrip strength, gait speed, knee extensor muscle power, physical performance, muscle mass using DEXA, quality of life, activities of daily living, sarcopenia screening questionnaire, nutritional assessment will be evaluated on baseline, 12-weeks and 24-weeks after intervention |
| Who can participate | Inclusion Criteria: * patients older than 65 years and under 90 years * patients who meet the criteria for the Asian Working Group for Sarcopenia (AWGS) 2019 * patients who had metabolic syndrome Exclusion Criteria: * patients with less than estimated glomerular filtration rate (eGFR) 30 * patients with musculoskeletal or chronic lung disease incapable of exercise * patients with untreated or uncontrolled cardiovascular disease which may affect muscle mass or performing exercise * patients less than 5 years after treatment of malignant tumor * patients with liver cirrhosis, diabetes and other chronic disease * patients who cannot perform combined exercise nutrition intervention for other reasons |
| Ages | 65 Years to 90 Years |
| Sex | All |
| Lead sponsor | Seoul Bumin Hospital |
| Locations | Seoul, South Korea |
| Start date | 2022-03-29 |
| NCT ID | NCT06654648 |
| Official listing | https://clinicaltrials.gov/study/NCT06654648 |