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Comparing SBRT to CRT in Patients With Spinal Metastases

This is a single institutional registry-based, prospective, observational study to describe radiation oncologists' decision making during evaluation of patients and to compare real-world outcomes of SBRT vs CRT. A registry-based trial involves observing the effect of something without manipulating it.

Condition(s)Spinal Metastases
StatusRecruiting
Study typeObservational
SummaryThis is a single institutional registry-based, prospective, observational study to describe radiation oncologists' decision making during evaluation of patients and to compare real-world outcomes of SBRT vs CRT. A registry-based trial involves observing the effect of something without manipulating it.
Who can participateInclusion Criteria: * Adults 18 years of age or older. * Patients seen at the Princess Margaret Cancer Centre with painful spinal metastases amenable to radiation treatment. * Confirmation of diagnosis: a) Known/documented prior histological cancer diagnosis * Able to provide written consent * ECOG performance status 0-3 Exclusion Criteria: * Prior radiotherapy, with fields overlapping, resulting in excessive doses to organs at risk * Lymphoma, myeloma or germ cell malignancies
Ages18 Years to 100 Years
SexAll
Lead sponsorUniversity Health Network, Toronto
LocationsToronto, Ontario, Canada
Start date2022-12-12
NCT IDNCT05589701
Official listinghttps://clinicaltrials.gov/study/NCT05589701

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