Comparing Two Prophylactic Antibiotic Protocols in Women With Term Prolonged Pre-labor Rup
This randomized prospective trial aimed to compare 2 prophylactic antibiotic regiment (ampicillin alone versus ampicillin plus gentamycin) in term prolonged pre-labor rupture of membrane and in preterm deliveries and examine related obstetrical outcome and infectious morbidity
| Condition(s) | Preterm Labor With Preterm Delivery, Premature Rupture of Membranes Prolonged |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | This randomized prospective trial aimed to compare 2 prophylactic antibiotic regiment (ampicillin alone versus ampicillin plus gentamycin) in term prolonged pre-labor rupture of membrane and in preterm deliveries and examine related obstetrical outcome and infectious morbidity |
| Who can participate | Inclusion Criteria: maternal age \> 18 years singleton pregnancy vertex presentation prolonged \>18 h prom or preterm delivery \- Exclusion Criteria: * GBS carrier * preterm premature rupture of membrane for conservative treatment * intra-uterine fetal death fetal major anomaly * drug allergy for the antibiotic in use in this study * women receiving antibiotic treatment for other infection such as urinary tract infection |
| Ages | 18 Years to 48 Years |
| Sex | Female |
| Accepts healthy volunteers | Yes |
| Lead sponsor | Western Galilee Hospital-Nahariya |
| Locations | Nahariya, Israel |
| Start date | 2022-11-25 |
| NCT ID | NCT05469984 |
| Official listing | https://clinicaltrials.gov/study/NCT05469984 |