Comparison of Customized Allogenic Versus Autogenous Bone Block Graft for Alveolar Ridge A
The aim of this study is to determine whether jawbone augmentations using allogeneic and autogenous bone blocks lead to comparable three-dimensional clinical and radiological outcomes. In addition, the study seeks to investigate whether there are differences regarding safety, biocompatibility, complications, and PROMs.
| Condition(s) | Alveolar Bone Loss |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The aim of this study is to determine whether jawbone augmentations using allogeneic and autogenous bone blocks lead to comparable three-dimensional clinical and radiological outcomes. In addition, the study seeks to investigate whether there are differences regarding safety, biocompatibility, complications, and PROMs. Furthermore, it aims to clarify whether differences exist between the two groups with respect to implant condition (one year after implantation and during annual follow-ups for up to five years). |
| Who can participate | INCLUSION CRITERIA * 1-4 missing teeth that need to be replaced with dental implants * Bone ridge width insufficient for dental implant placement; \<5 mm of width as measured in a cone beam computed tomography at the ideal prosthetic position * Medically healthy with no known allergies to antibiotics * Non-smoker or light smoker (\< 10) or previous smoker who had quit for 5 years or more * Periodontal health, as confirmed by clinical examination (Full mouth bleeding score and full mouth plaque score \< 25%) and at least one neighboring natural tooth to the defect site(s) * Age of 18 or above EXCLUSION CRITERIA * All contraindications against implant treatment or augmentative procedures (e.g., advanced systemic diseases, corticosteroid medication, immunodeficiency, pregnancy, intention to b |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | Medical University of Graz |
| Locations | Graz, Styria, Austria |
| Start date | 2025-04-01 |
| NCT ID | NCT07419269 |
| Official listing | https://clinicaltrials.gov/study/NCT07419269 |