Comparison of Serratus Intercostal Plane Blcok With Erector Spinae Plane Block for Open Ne
Effective postoperative pain management following open nephrectomy remains a significant clinical challenge. Inadequate pain control after this procedure may lead to impaired respiratory function, delayed mobilization, prolonged hospital stay, increased opioid consumption, and a higher incidence of postoperative compli
| Condition(s) | Post Operative Pain, Open Nephrectomy |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | Effective postoperative pain management following open nephrectomy remains a significant clinical challenge. Inadequate pain control after this procedure may lead to impaired respiratory function, delayed mobilization, prolonged hospital stay, increased opioid consumption, and a higher incidence of postoperative complications. Therefore, optimizing postoperative analgesia while minimizing opioid-related adverse effects is a key objective in perioperative care for patients undergoing open nephrectomy Traditionally, postoperative pain following open nephrectomy has been managed using systemic opioids, epidural analgesia, or paravertebral blocks. Ultrasound-guided fascial plane blocks have emerged as valuable alternatives in modern regional anesthesia due to their simplicity, safety profile, |
| Who can participate | Inclusion Criteria: 1. Patients scheduled for elective open nephrectomy under general anesthesia via flank incision . 2. Adult patients aged 18-65 years. 3. Patients with an American Society of Anesthesiologists (ASA) physical status I to III. Exclusion Criteria: 1. Patient refusal. 2. Allergy to local anesthetics and patient with infection at the injection site of block. 3. Coagulation disorders or ongoing anticoagulant therapy. 4. Patients receiving opioids for chronic analgesic therapy (cancer, addiction). 5. Cognitive impairment preventing pain scoring. 6. Neurological or psychiatric disorders affecting pain assessment. |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Lead sponsor | Fayoum University Hospital |
| Locations | Al Fayyum, Egypt |
| Start date | 2026-04-10 |
| NCT ID | NCT07556536 |
| Official listing | https://clinicaltrials.gov/study/NCT07556536 |