Comparison of Two-Position and Four-Position Cervical Injection Techniques for Sentinel Ly
This clinical trial evaluates lymph node mapping in newly diagnosed endometrial cancer patients undergoing surgery. The standard technique uses a 2-point methylene blue cervical injection. The study aims to determine if increasing injection points improves mapping success.
| Condition(s) | Endometrial Neoplasms, Endometrial Cancer Stage I, Sentinel Lymph Node, Metastasis |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | This clinical trial evaluates lymph node mapping in newly diagnosed endometrial cancer patients undergoing surgery. The standard technique uses a 2-point methylene blue cervical injection. The study aims to determine if increasing injection points improves mapping success. |
| Who can participate | Inclusion Criteria: * Individuals diagnosed with stage I endometrial cancer based on CT and PET-CT imaging. * Individuals with a pathologically confirmed diagnosis of stage I endometrial cancer. Exclusion Criteria: Medical Conditions * Individuals diagnosed with dementia. * Individuals with allergies to methylene blue or iodine. * Individuals who have received active treatment for another malignancy within the past five years. * Inability to successfully perform PLD (pelvic lymphadenectomy) or history of prior PLD. * Women with multiple and confluent lymph nodes identified as positive on FDG-PET/CT (such cases are not considered stage I). Cancer-Related Conditions * Individuals with clinically or radiologically identified positive lymph nodes or metastatic disease. * Individuals with a his |
| Ages | 18 Years to 75 Years |
| Sex | Female |
| Lead sponsor | Dokuz Eylul University |
| Locations | Ankara, Turkey (Türkiye); Izmir, Turkey (Türkiye) |
| Start date | 2025-05-01 |
| NCT ID | NCT07040657 |
| Official listing | https://clinicaltrials.gov/study/NCT07040657 |