Coronary Microvascular Dysfunction in Angina Patients With Non-obstructive Coronary Artery
The goal of this observational study is to explore the incidence and effect on prognosis of coronary microvascular dysfunction in patients present of stable anginal symptoms, a clinical indication for invasive coronary angiography, and no hemodynamically significant epicardial coronary artery disease, defined as fracti
| Condition(s) | Angina Patients With Non-obstructive Coronary Artery Disease, Coronary Microvascular Dysfunction, Index of Microvascular Resistance |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | The goal of this observational study is to explore the incidence and effect on prognosis of coronary microvascular dysfunction in patients present of stable anginal symptoms, a clinical indication for invasive coronary angiography, and no hemodynamically significant epicardial coronary artery disease, defined as fractional flow reserve (FFR) \>0.80. |
| Who can participate | Inclusion Criteria: * presence of stable anginal symptoms, a clinical indication for invasive coronary angiography, and no hemodynamically significant epicardial coronary artery disease, defined as fractional flow reserve (FFR) \>0.80 Exclusion Criteria: 1. acute myocardial infarction 2. significant valvular heart disease 3. advanced chronic kidney disease 4. patients with significant epicardial coronary artery stenosis (\>70% in major vessels by diagnostic coronary angiography) needing percutaneous coronary intervention 5. patients unable to provide written informed consent |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | China-Japan Friendship Hospital |
| Locations | Beijing, Beijing Municipality, China |
| Start date | 2023-07-01 |
| NCT ID | NCT06503640 |
| Official listing | https://clinicaltrials.gov/study/NCT06503640 |