CPAP for Esophageal Cancer With Radiotherapy
The goal of this clinical trial is to test the use of CPAP in patients with esophgaeal cancer undergoing radiotherapy. The main questions it aims to answer are: * does use of CPAP decrease exposure of normal lung to radiation? * does use of CPAP decrease exposure of normal heart to radiation? Participants will undergo
| Condition(s) | Esophageal Cancer |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The goal of this clinical trial is to test the use of CPAP in patients with esophgaeal cancer undergoing radiotherapy. The main questions it aims to answer are: * does use of CPAP decrease exposure of normal lung to radiation? * does use of CPAP decrease exposure of normal heart to radiation? Participants will undergo simulation twice: * with CPAP * without CPAP |
| Who can participate | Inclusion Criteria: 1. Diagnosis of cancer, with a tumor (primary or secondary) in the esophagus including tumors in the esophagus-stomach junction. 2. Age ≥ 18 3. Planned RT treatment 4. The level of functioning ≥ 60 on the Karnofsky scale 5. Life expectancy ≥ two months 6. All patients must understand the informed consent form document and sign it of their own free will before any test/procedure related to the study is performed. 7. Able to undergo simulation and radiation with CPAP 8. Candidate patients can be recruited to receive definitive, palliative or pre-operative radiation, with or without chemotherapy. Exclusion Criteria: A person who meets any of the following exclusion criteria will not be able to participate in the study: 1. Pregnancy or breastfeeding 2. Significant comorbidi |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | Sheba Medical Center |
| Locations | Ramat Gan, Israel |
| Start date | 2023-08-21 |
| NCT ID | NCT06037902 |
| Official listing | https://clinicaltrials.gov/study/NCT06037902 |