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Creatine Supplementation During GLP-1a Therapy

GLP-1 receptor agonists are effective for weight loss, but significant muscle mass is lost as a proportion of this weight loss. This study combines resistance-training and creatine supplementation to try to prevent this loss of muscle mass.

Condition(s)Sarcopenia
StatusRecruiting
PhaseNA
Study typeInterventional
SummaryGLP-1 receptor agonists are effective for weight loss, but significant muscle mass is lost as a proportion of this weight loss. This study combines resistance-training and creatine supplementation to try to prevent this loss of muscle mass.
Who can participateInclusion Criteria: * Starting GLP-1 agonist therapy * 18 years of age or older Exclusion Criteria: * Positive answers to a screening questionnaire for physical activity safety (the Get Active Questionnaire)
Ages18 Years
SexAll
Accepts healthy volunteersYes
Lead sponsorUniversity of Saskatchewan
LocationsSaskatoon, SK - Saskatchewan, Canada
Start date2026-05-25
NCT IDNCT07625202
Official listinghttps://clinicaltrials.gov/study/NCT07625202

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