Danish Prognostic Research on Embryonic Diagnostics Involving Chromosomal Testing.
The study aim is to evaluate whether testing embryos for chromosomal abnormalities (known as aneuploidy) can aid in embryo selection. If so, transfer of embryos that will fail to implant, miscarry or lead to birth of affected children, can be reduces. This would reduce the risk of miscarriage and increase the chance of
| Condition(s) | Aneuploidy |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | The study aim is to evaluate whether testing embryos for chromosomal abnormalities (known as aneuploidy) can aid in embryo selection. If so, transfer of embryos that will fail to implant, miscarry or lead to birth of affected children, can be reduces. This would reduce the risk of miscarriage and increase the chance of healthy live birth per embryo transfer, which in turn would reduce the time and economical, physical and psychological cost associated with fertility treatment. The method of genetically testing embryos for aneuploidy is know as preimplantation genetic testing for aneuploidy (PGT-A). It entails testing a biopsy from preimplantation embryos generated from assisted reproductive technology (ART) from which DNA can be analyzed. Another potential source of embryonic DNA is the sp |
| Who can participate | Inclusion Criteria: * Undergoing preimplantation genetic testing for monogenic disorders (PGT-M) Exclusion Criteria: * None |
| Sex | All |
| Lead sponsor | Christian Liebst Frisk Toft |
| Locations | Aalborg, Denmark |
| Start date | 2025-04-22 |
| NCT ID | NCT06915311 |
| Official listing | https://clinicaltrials.gov/study/NCT06915311 |