Developing a Novel Human Laboratory Paradigm for AUD Medication Screening
The intent of the study is to develop two versions of the 'ability to resist' drinking model designed to screen Alcohol Use Disorder (AUD) medications.
| Condition(s) | Alcohol Use Disorder |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The intent of the study is to develop two versions of the 'ability to resist' drinking model designed to screen Alcohol Use Disorder (AUD) medications. |
| Who can participate | Inclusion Criteria: 1. Provision of signed and dated informed consent form; 2. Male or Female Age 21-65; 3. Able to read and write English; 4. Meets DSM-5 criteria for current (past 6 months); 5. Drinking criteria: Males - Drinks \> 28 drinks per week and exceeds 4 drinks per day at least once per week; Females -Drinks \> 14 drinks per week and exceeds 3 drinks per day at least once per week. Must meet drinking criteria during 30-day period prior to baseline; 6) Laboratory sessions will be scheduled such that participants will not have major responsibilities on the following day which might limit drinking during the self-administration session (e.g., job interview, exam). Exclusion Criteria: 1. Participants with any significant current medical conditions (neurological, cardiovascular, endo |
| Ages | 21 Years to 65 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | Yale University |
| Locations | New Haven, Connecticut, United States |
| Start date | 2024-11-01 |
| NCT ID | NCT06489782 |
| Official listing | https://clinicaltrials.gov/study/NCT06489782 |