Development of Optimal Sensory Feedback Strategies to Maximize Function After Tetraplegia
The goal of this clinical trial is to learn more about how stimulating the nerves involved in sensation (either in the limbs or in the brain) can be used to restore sensation in participants who have a spinal cord injury. Participants in this study will have already been enrolled in the "Reconnecting the Hand and Arm t
| Condition(s) | Spinal Cord Injury Cervical, Spinal Cord Injuries (Complete and Incomplete) |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The goal of this clinical trial is to learn more about how stimulating the nerves involved in sensation (either in the limbs or in the brain) can be used to restore sensation in participants who have a spinal cord injury. Participants in this study will have already been enrolled in the "Reconnecting the Hand and Arm to the Brain (ReHAB)" study, and received small electrodes in a part of the brain that is involved in sensing touch and pressure in the hand. The ReHAB study participants will also have received electrodes around the nerves in their arm. In this clinical trial, participants will receive two types of electrical stimulation: * Intracortical microstimulation (ICMS) which involves sending small electrical pulses to the part of the brain that processes sensation. * Peripheral nerve |
| Who can participate | Inclusion Criteria: 1. Enrolled in the ReHAB clinical trial and received ReHAB system components via implantation surgery. 2. Willingness and availability to follow the study protocol. Exclusion Criteria: 1. Lack of function or operability of all implanted ReHAB system components 2. Severe pain or other chronic medical condition that would prevent the participant from completing study-related activities |
| Ages | 22 Years to 65 Years |
| Sex | All |
| Lead sponsor | Case Western Reserve University |
| Locations | Cleveland, Ohio, United States |
| Start date | 2026-01-13 |
| NCT ID | NCT07225582 |
| Official listing | https://clinicaltrials.gov/study/NCT07225582 |