Effect of Giving Reduced Fluid in Children After Trauma
This study is designed to help decide how much intravenous (IV) fluid should be given to pediatric trauma patients. No standard currently exists for managing fluids in critically ill pediatric trauma patients, and many fluid strategies are now in practice. For decades, trauma patients got high volumes of IV fluid. Rece
| Condition(s) | Critical Illness, Pediatrics, General Surgery, Fluid Therapy, Wounds and Injuries |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | This study is designed to help decide how much intravenous (IV) fluid should be given to pediatric trauma patients. No standard currently exists for managing fluids in critically ill pediatric trauma patients, and many fluid strategies are now in practice. For decades, trauma patients got high volumes of IV fluid. Recent studies in adults show that patients actually do better by giving less fluid. The investigators do not know if this is true in children and this study is designed to answer that question and provide guidelines for IV fluid management in children after trauma. |
| Who can participate | Inclusion Criteria: * Trauma patients older than 6 months and younger than 15 years admitted to the pediatric intensive care unit (PICU) * Patients admitted to the PICU directly from the Emergency Department (ED) * Patients admitted to the PICU from the operating room (OR) * Patients transferred to PICU from outside facility ED (need to have been in ED 12 hours or less) Exclusion Criteria: * Patients transferred to PICU from outside PICU or inpatient floor * Patients transferred to PICU from outside facility ED if \>12 hours * Patients expected to be discharged from the PICU within 24 hours * Patient with congenital heart disease as defined by a congenital cardiac defect requiring surgery or medication * Patient with diagnosis of chronic cardiac condition (e.g. hypertension, cardiac arrhyt |
| Ages | 6 Months to 15 Years |
| Sex | All |
| Lead sponsor | Columbia University |
| Locations | Buffalo, New York, United States; New York, New York, United States; Rochester, New York, United States; Memphis, Tennessee, United States |
| Start date | 2018-08-27 |
| NCT ID | NCT04201704 |
| Official listing | https://clinicaltrials.gov/study/NCT04201704 |