Effectiveness of Probiotic Gummies in Relieving Allergic Rhinitis in Children
To evaluate the effect of probiotic gummies on serum metabolite levels, clinical efficacy, and regulation of gut microbiota in children with allergic rhinitis compared with placebo.
| Condition(s) | Children With Allergic Rhinitis |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | To evaluate the effect of probiotic gummies on serum metabolite levels, clinical efficacy, and regulation of gut microbiota in children with allergic rhinitis compared with placebo. |
| Who can participate | Inclusion Criteria: 1. Voluntary, written, signed informed consent to participate in this study; 2. be able to complete the study in accordance with the requirements of the test protocol; 3. Age 4-14 years old; 4. Meet the diagnostic criteria for allergic rhinitis established in the Guidelines for the Diagnosis and Treatment of Allergic Rhinitis in Children (2022 Revised Edition); 5. Symptoms: 2 or more symptoms: sneezing, watery discharge, nasal itching and nasal congestion and other symptoms last or accumulate for more than 1 hour per day, and may be accompanied by eye symptoms such as itching, watery eyes and red eyes; 6. Signs: pale and edema of the nasal mucosa, which may be accompanied by watery discharge; Exclusion Criteria: 1. Drugs that affect the intestinal flora (including antim |
| Ages | 4 Years to 14 Years |
| Sex | All |
| Lead sponsor | Wecare Probiotics Co., Ltd. |
| Locations | Luoyang, Henan, China |
| Start date | 2025-03-10 |
| NCT ID | NCT06885632 |
| Official listing | https://clinicaltrials.gov/study/NCT06885632 |