Effects of Collagen Peptide Supplementation on Connective Tissue Remodeling, Functional Ou
Recruiting will be performed via checking the calendar for scheduled TKA procedures in the \> 8 weeks by clinical staff in the UAMS orthopedic clinic. Clinic staff will look for basic inclusion/exclusion criteria in the EMR for those patients. Clinic staff will either contact directly or send contact information to the
| Condition(s) | Knee Osteoarthritis |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | Recruiting will be performed via checking the calendar for scheduled TKA procedures in the \> 8 weeks by clinical staff in the UAMS orthopedic clinic. Clinic staff will look for basic inclusion/exclusion criteria in the EMR for those patients. Clinic staff will either contact directly or send contact information to the PI of this study to contact for recruitment purposes. During the initial phone call, study staff will review inclusion/exclusion criteria to verify eligibility and will discuss study specifics and send a link to the current informed consent form located on the UAMS REDCap server. If the subject wishes to enroll, they will do so via electronic consent through REDCap. REDCap will notify study staff that the consent was signed, then study staff will schedule initial baseline st |
| Who can participate | Inclusion Criteria: * Males and Females, 50 to 75 years old * With a body mass index of 20.0 to 39.9 kg/m2 * Diagnosed with primary osteoarthritis * Scheduled for a TKA at UAMS (two months prior to surgery) at UAMS * Live near Little Rock and scheduled to attend physical therapy in Little Rock * COVID-19 negative and/or asymptomatic. Exclusion Criteria: * Previously sustained serious knee injury or surgery to ACL in TKA knee * Females not postmenopausal * Having undergone hormone replacement therapy in the last 12 months. * Active diagnosis of blood borne infectious disease |
| Ages | 50 Years to 75 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | University of Arkansas |
| Locations | Little Rock, Arkansas, United States |
| Start date | 2026-05-01 |
| NCT ID | NCT05823727 |
| Official listing | https://clinicaltrials.gov/study/NCT05823727 |