Effects of Physical Activity and Fitness, Cardiovascular- and Psychosocial Health on Medic
This prospective observational study aims to investigate the association between physical activity and clinical pregnancy rates in women undergoing medically assisted reproduction. Additionally, it evaluates how cardiorespiratory fitness, cardiovascular health, psychosocial factors, sleep quality, stress, and cognitive
| Condition(s) | Infertility, Female |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | This prospective observational study aims to investigate the association between physical activity and clinical pregnancy rates in women undergoing medically assisted reproduction. Additionally, it evaluates how cardiorespiratory fitness, cardiovascular health, psychosocial factors, sleep quality, stress, and cognitive function relate to reproductive outcomes. |
| Who can participate | Inclusion Criteria: * Voluntary written informed consent of the participant has been obtained prior to any screening procedures * Age 18-43 * Planning to undergo MAR (eg, IUI, IVF, ICSI) - Physically able to cycle for cardiopulmonary exercise testing (CPET) Exclusion Criteria: * Any reduction in general state of health preventing from performing hormonal stimulation for MAR * Absolute and relative contraindications for cardiopulmonary exercise testing (CPET) - No pregnancy at initial screening - Current illicit drug abuse including daily marijuana and CBD consumption (alcohol ≤2 drinks per day allowed) * Any kind of severe chronic disease (e.g. severe heart failure, active cancer disease) * Severe renal impairment (e.g. estimated glomerular filtration rate \<30 ml/min/m2) * Known liver cir |
| Ages | 18 Years to 43 Years |
| Sex | Female |
| Accepts healthy volunteers | Yes |
| Lead sponsor | University Hospital, Basel, Switzerland |
| Locations | Basel, Switzerland |
| Start date | 2026-01-16 |
| NCT ID | NCT07321665 |
| Official listing | https://clinicaltrials.gov/study/NCT07321665 |