Effects of Progressive Restricted Blood Flow Exercises in Post Total Knee Arthroplasty
Total knee arthroplasty (TKA) is a commonly performed procedure for advanced knee osteoarthritis. Despite successful surgery, many patients experience postoperative impairments including pain, reduced range of motion (ROM), swelling, impaired proprioception, and kinesiophobia, which may delay functional recovery. Conve
| Condition(s) | Total Knee Arthroplasty Recovery |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | Total knee arthroplasty (TKA) is a commonly performed procedure for advanced knee osteoarthritis. Despite successful surgery, many patients experience postoperative impairments including pain, reduced range of motion (ROM), swelling, impaired proprioception, and kinesiophobia, which may delay functional recovery. Conventional physiotherapy is the standard rehabilitation approach following TKA; however, high-load strengthening exercises are often limited in the early postoperative phase due to pain and reduced tolerance. Blood flow restriction (BFR) exercise is an emerging rehabilitation technique that enables low-load exercise to produce strength adaptations similar to high-intensity training. While evidence supports its effectiveness for improving muscle strength, its effects on other out |
| Who can participate | Inclusion Criteria: 1. Patients of age 50-65 years. 2. Primary unilateral TKA due to osteoarthritis. 3. Individuals with mild to moderate postoperative pain (NPRS score 4-7). 4. Minimum active knee flexion of 30° \& an extension lag of no more than 15°. 5. Patients should be medically stable, cognitively able to follow instructions in Urdu or english, and willing to provide written informed consent Exclusion Criteria: 1. History of deep vein thrombosis within the last six months. 2. Peripheral vascular disease and active infection. 3. Severe cardiovascular conditions 4. Neurological disorders affecting lower limb function |
| Ages | 50 Years to 65 Years |
| Sex | All |
| Lead sponsor | Lahore University of Biological and Applied Sciences |
| Locations | Lahore, Punjab Province, Pakistan |
| Start date | 2026-05-25 |
| NCT ID | NCT07601906 |
| Official listing | https://clinicaltrials.gov/study/NCT07601906 |