Efficacy and Safety of Transcranial Temporal Interference Stimulation (tTIS) for Neuropath
This is an open-label, single-arm, single-center prospective pilot study to assess the efficacy and safety of transcranial temperol interference stimulation in patients with neuromyelitis optica spectrum disorder (NMOSD) complicated by neuropathic pain in China.
| Condition(s) | NMO Spectrum Disorder |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | This is an open-label, single-arm, single-center prospective pilot study to assess the efficacy and safety of transcranial temperol interference stimulation in patients with neuromyelitis optica spectrum disorder (NMOSD) complicated by neuropathic pain in China. |
| Who can participate | Inclusion Criteria: * Patients diagnosed with NMOSD in accordance with the criteria of the International Panel for Neuromyelitis Optica Diagnosis (IPND). * Patients were complicated with neuropathic pain, with a DN4 score ≥ 4. * NRS score for pain ≥ 4 points, and neuropathic pain has persisted for more than 3 months. * Patients receiving biological therapy and/or prednisone at a stable dose, with no adjustment of the treatment plan within 30 days before enrollment. * Patients who have not adjusted any combination of standard analgesic drugs (including antiepileptic drugs, antidepressants, and opioid drugs) within 30 days before enrollment. * Patients or their family members who have signed a written informed consent form. Exclusion Criteria: * Subjects participating in other clinical studi |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Lead sponsor | Tang-Du Hospital |
| Locations | Xi'an, Shaanxi, China |
| Start date | 2025-12-08 |
| NCT ID | NCT07377305 |
| Official listing | https://clinicaltrials.gov/study/NCT07377305 |