Efficacy of rTMS Treatment After Spinal Cord Injury
There is accumulating evidence that neuromodulation by repetitive transcranial magnetic stimulation (rTMS) of the motor cortex holds promise as a treatment for rehabilitation of motor function following a spinal cord injury. This study is designed to assess the clinical potential of non-invasive stimulation of the prim
| Condition(s) | Spinal Cord Injuries, Myelopathy |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | There is accumulating evidence that neuromodulation by repetitive transcranial magnetic stimulation (rTMS) of the motor cortex holds promise as a treatment for rehabilitation of motor function following a spinal cord injury. This study is designed to assess the clinical potential of non-invasive stimulation of the primary motor cortex to improve motor functions.The results will help to evaluate the clinical relevance of motor cortex stimulation for motor functions in patients with spinal cord injury. The outcomes of this study could potentially support the initiation of a larger clinical trial and the development of a new routine treatment. |
| Who can participate | Inclusion Criteria: * Age over 18 years and less than 80 years * Chronic patients with an incomplete cervical and/or thoracic spinal cord injury (traumatic and non-traumatic) affecting upper and/or lower extremities (i.e., C4-T12 and classified as ASIA C or D) (Figure 138). * Capable and willing to provide informed consent and able to adhere to the treatment schedule * Patients who can be followed for the whole duration of the study 6.3 Exclusion criteria * Contraindication to rTMS: * past severe head trauma * history of epilepsy or ongoing epilepsy * active cerebral tumor * intracranial hypertension * implanted ferromagnetic devices such as cardiac pacemaker and neurostimulator and cochlear implants * pregnancy or lactation. * Any clinically significant or unstable medical or psychiatric |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | Oslo University Hospital |
| Locations | Oslo, Norway |
| Start date | 2024-01-15 |
| NCT ID | NCT06464744 |
| Official listing | https://clinicaltrials.gov/study/NCT06464744 |