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Ejaculatory-Sparing HoLEP vs Standard HoLEP

The objective of this study is to compare a new surgical technique for HoLEP that will allow for sparing of ejaculation post-HoLEP.

Condition(s)Enlarged Prostate (BPH), Enlarged Prostate With Lower Urinary Tract Symptoms
StatusRecruiting
PhaseNA
Study typeInterventional
SummaryThe objective of this study is to compare a new surgical technique for HoLEP that will allow for sparing of ejaculation post-HoLEP.
Who can participateInclusion Criteria: \- Patients who are sexually active with antegrade ejaculation who are undergoing HoLEP for the treatment of bothersome lower urinary tract symptoms. Exclusion Criteria: * Patients with pre-existing retrograde ejaculation * Patients who are not sexually active * Patients with indwelling urinary catheter prior to surgery, neurological disease, or history of prior prostatic/urethral surgery that may impact ejaculation * Patients who lack decisional capacity * Patients unable to read/speak English
Ages18 Years to 100 Years
SexMale
Accepts healthy volunteersYes
Lead sponsorNorthwestern University
LocationsChicago, Illinois, United States
Start date2026-06
NCT IDNCT07631286
Official listinghttps://clinicaltrials.gov/study/NCT07631286

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