Electrophysiological Representations of Odor in the Human Brain Study 1
Investigating representations of odor intensity in human piriform cortex. To identify a neural representation of perceived odor intensity, it is necessary to dissociate stimulus concentration from perceived intensity. Experiments for this aim will measure human perceptual responses while manipulating intensity independ
| Condition(s) | Odor Intensity Ratings |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | Investigating representations of odor intensity in human piriform cortex. To identify a neural representation of perceived odor intensity, it is necessary to dissociate stimulus concentration from perceived intensity. Experiments for this aim will measure human perceptual responses while manipulating intensity independently from concentration using two complementary approaches. In Experiment 1A, we will match perceived intensities across odors of different concentrations, allowing us to identify a neural representation of intensity that is independent of stimulus identity and concentration. In Experiment 1B, we will create conditions of different perceived intensity over constant odor stimuli using adaptation. Approaching the same question from different angles will strengthen the robustne |
| Who can participate | Inclusion Criteria: * Ages 12 to 65, english speaker, patients undergoing brain surgery for treatment of medically intractable epilepsy Exclusion Criteria: * screening for history of smell or taste problems |
| Ages | 12 Years to 65 Years |
| Sex | All |
| Lead sponsor | Northwestern University |
| Locations | Chicago, Illinois, United States |
| Start date | 2024-04-01 |
| NCT ID | NCT06769464 |
| Official listing | https://clinicaltrials.gov/study/NCT06769464 |