Electrosurgical Modes for Endoscopic Submucosal Dissection in Peroral Endoscopic Esophagea
Peroral endoscopic esophagel myotomy (POEM) is a third space endoscopy technique that depends on creating a submucosal tunnel to expose the esophageal muscle and eventually perform an esophageal myotomy. Submucosal dissection can be performed using numerous electrosurgical modes. Spray coagulation has been anecdotally
| Condition(s) | Achalasia, Achalasia Cardia |
|---|---|
| Status | Recruiting |
| Phase | Phase 3 |
| Study type | Interventional |
| Summary | Peroral endoscopic esophagel myotomy (POEM) is a third space endoscopy technique that depends on creating a submucosal tunnel to expose the esophageal muscle and eventually perform an esophageal myotomy. Submucosal dissection can be performed using numerous electrosurgical modes. Spray coagulation has been anecdotally favored by many endoscopists due to its high coagulation power and assumed safety. Recently, Precisect mode has been developed, it has theoretical advantages of very minimal tissue penetration and minimal to no charring effect. In this trial, the investigators compare the efficacy and safety of both electrosurgical modes in POEM procedures. |
| Who can participate | Inclusion Criteria: * Patients undergoing POEM procedure for any esophageal motility disorder * Esophageal motility disorder confirmed by high-resolution manometry and gastroscopy Exclusion Criteria: * Esophageal varices * Esophageal neoplasms * Non-correctable coagulopathy * Failure to provide an informed consent |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | Cairo University |
| Locations | Cairo, Egypt |
| Start date | 2024-03-16 |
| NCT ID | NCT06189859 |
| Official listing | https://clinicaltrials.gov/study/NCT06189859 |