EMG-guided Botox Injection Versus Conventional Botox Injection in Gummy Smile Patients
The goal of this clinical trial is to compare the effect of EMG-guided Botox injection with conventional Botox injection in Yonsei point, in patients with excessive gingival display. The main question it aims to answer is: • Does the use of electromyography (EMG) as a guide during Botox injection for patients with gumm
| Condition(s) | Excessive Gingival Display |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The goal of this clinical trial is to compare the effect of EMG-guided Botox injection with conventional Botox injection in Yonsei point, in patients with excessive gingival display. The main question it aims to answer is: • Does the use of electromyography (EMG) as a guide during Botox injection for patients with gummy smile has better effect than conventional injection in Yonsei point? Participants will be randomized in equal proportions between intervention and control groups. * Preoperative assessment of amount of gingival display, lip length (philtrum and vermilion length), and smile type. * For the intervention group, EMG readings will be done in Clinical Neurophysiology Department, Kasr Al-Ainy Hospital EMG-guided Botox injection (Intervention group). Conventional Botox injection in |
| Who can participate | Inclusion Criteria: * Patients with excessive gingival display. * Patients with esthetic concerns. * Patients with mild to moderate VME (vertical maxillary excess). * Normal clinical crown dimensions. * Patients aged 18 to 50. * Systemically healthy patients. * Non-smokers. Exclusion Criteria: * Patients with severe VME (vertical maxillary excess). * Pregnant and breastfeeding women. * Patients with gingival inflammation and/or enlargement. * Inflammation or infection at the site of injection. * Patients with known allergy to any of the components of Botox (i.e., saline, human albumin, lactose and sodium succinate). * Patients using anticholinesterase or other agents affecting neuromuscular transmission. * Psychologically unstable patients or those who have unrealistic expectations and que |
| Ages | 18 Years to 50 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | Cairo University |
| Locations | Cairo, Egypt |
| Start date | 2024-11-01 |
| NCT ID | NCT06075134 |
| Official listing | https://clinicaltrials.gov/study/NCT06075134 |