Endothelial Dysfunction and Non-cardiac Surgery
Endothelial dysfunction is a cardiovascular disease hallmark. After non-cardiac surgery, cardiovascular events correlate with surgical outcomes. Understanding the role of endothelial function in these events is crucial. This research aims to study endothelial function and its association with cardiovascular events.
| Condition(s) | Surgery, Cardiac Death, Stroke, Myocardial Injury |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | Endothelial dysfunction is a cardiovascular disease hallmark. After non-cardiac surgery, cardiovascular events correlate with surgical outcomes. Understanding the role of endothelial function in these events is crucial. This research aims to study endothelial function and its association with cardiovascular events. |
| Who can participate | Inclusion Criteria: * Signed informed consent * Patients 45 years or older Exclusion Criteria: * Refuse to participate in the study * Myocardial injury or acute myocardial infarction less than two weeks ago * Patients who expect less than 2 days of hospitalization * Patients in whom the troponin elevation is attributed to a secondary cause (for example, sepsis, pulmonary thromboembolism, electrical cardioversion, etc.) * Use of chemotherapy less than 2 weeks ago |
| Ages | 45 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | University of Chile |
| Locations | Independencia, Santiago Metropolitan, Chile |
| Start date | 2023-03-25 |
| NCT ID | NCT05778981 |
| Official listing | https://clinicaltrials.gov/study/NCT05778981 |