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EUS-guided Celiac Plexus Block vs. Sham in Chronic Pancreatitis

The aim of this randomized trial is to assess the efficacy of EUS-CPB in the alleviation of abdominal pain in patients with chronic pancreatitis.

Condition(s)Chronic Pancreatitis
StatusRecruiting
PhaseNA
Study typeInterventional
SummaryThe aim of this randomized trial is to assess the efficacy of EUS-CPB in the alleviation of abdominal pain in patients with chronic pancreatitis.
Who can participateInclusion Criteria: * Age ≥ 18 years * Abdominal pain of at least 3 months duration and a VAS score ≥ 3, with or without the use of narcotic analgesics. * Diagnosis of chronic pancreatitis on EUS examination, with ≥ 5 features on EUS. * No other cause of abdominal pain Exclusion Criteria: * Age \< 18 years. * History of prior EUS-CPB. * Use of anticoagulants that cannot be discontinued for the procedure. * Clinically significant allergy to bupivacaine or triamcinolone. * Unable to obtain consent for the procedure from either the patient or LAR. * Intrauterine pregnancy.
Ages18 Years
SexAll
Lead sponsorOrlando Health, Inc.
LocationsOrlando, Florida, United States
Start date2023-12-07
NCT IDNCT06178315
Official listinghttps://clinicaltrials.gov/study/NCT06178315

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