Evaluating Presbyopia-Correcting IOLs in Complex Cataract Cases With Anterior Segment Abno
The goal of cataract surgery has evolved from simply restoring sight to providing clear and comfortable full-range vision. Traditionally, monofocal IOLs remain the routine choice for special cases with anterior segment abnormalities-such as lens subluxation, cataract with chronic uveitis, post-laser refractive cataract
| Condition(s) | Lens Diseases |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The goal of cataract surgery has evolved from simply restoring sight to providing clear and comfortable full-range vision. Traditionally, monofocal IOLs remain the routine choice for special cases with anterior segment abnormalities-such as lens subluxation, cataract with chronic uveitis, post-laser refractive cataract, and aphakia with insufficient capsular support. However, there is a growing demand among these patients for improved visual quality and spectacle independence.Currently, various presbyopia-correcting IOLs offer distinct advantages, providing more personalized options. The introduction and application of intraoperative optical coherence tomography (iOCT) ensures effective intraoperative monitoring. These advances make the precise implantation of presbyopia-correcting IOLs a |
| Who can participate | Inclusion Criteria: 1. Lens Subluxation Unilateral Implantation Group * Patients aged 18-80 years with diagnosed lens subluxation meeting surgical indications for lens surgery, enrolled unilaterally; * Informed consent for the study; * Ability to comply with full follow-up; * Kappa angle \<0.5 mm, total higher-order aberration root mean square (HOA RMS) within the central 4-mm corneal zone \<1 μm; * Mesopic natural pupil diameter between 3.0 mm and 5.5 mm; * Expected postoperative astigmatism ≤1.0 D, with target spherical equivalent between 0.00 D and ±0.75 D; * Subjective desire to improve full-range visual function. 2. Inactive Long-standing Anterior Uveitis with Cataract Unilateral Implantation Group * Patients aged 18-80 years with diagnosed inactive long-standing anterior uveitis (qui |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Lead sponsor | Second Affiliated Hospital, School of Medicine, Zhejiang University |
| Locations | Hangzhou, Zhejiang, China |
| Start date | 2025-11-17 |
| NCT ID | NCT07321756 |
| Official listing | https://clinicaltrials.gov/study/NCT07321756 |