Evaluation of First-void Urine as an Alternative to Cervical Sampling for Human Papillomav
Papillomaviruses are responsible for almost all cervical cancers. In France, there are more than 3000 new cases of cervical cancer each year and nearly 1000 deaths. One of the ways to prevent this cancer is screening by PCR on cervical sample for which national coverage rate remains very insufficient (\<60%). The invas
| Condition(s) | Uterine Cervical Cancer |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | Papillomaviruses are responsible for almost all cervical cancers. In France, there are more than 3000 new cases of cervical cancer each year and nearly 1000 deaths. One of the ways to prevent this cancer is screening by PCR on cervical sample for which national coverage rate remains very insufficient (\<60%). The invasive and uncomfortable nature of cervical sampling has been identified as a major obstacle to screening. In this context, an alternative sample, such as the first-void urine, seems to be judicious. Nevertheless, some studies have shown a lack of sensitivity of the HPV PCR test on urine. As underlined by the French National Authority for Health (HAS), this is mainly due to a lack of standardization of urine collection. In this study, the investigators therefore propose to evalu |
| Who can participate | Inclusion Criteria: * Female * Age between 30 and 65 * Consulting in the Gynecology-Obstetrics department for primary cervical cancer screening * Patient affiliated or entitled to a social security regimen * Patient who has received information about the study and expressed non-opposition Exclusion Criteria: \- |
| Ages | 30 Years to 65 Years |
| Sex | Female |
| Accepts healthy volunteers | Yes |
| Lead sponsor | Centre Hospitalier Universitaire de Saint Etienne |
| Locations | Saint-Etienne, France |
| Start date | 2024-05-23 |
| NCT ID | NCT06254846 |
| Official listing | https://clinicaltrials.gov/study/NCT06254846 |