Excessive Supraventricular Activity and Atrial Fibrillation
The aim of the proposed study is to determine if individuals with excessive supraventricular ectopic activity (ESVEA) on Holter recording should be subjected to prolonged screening with Event loop recorder in order to detect previously undiagnosed Atrial fibrillation / flutter. Other biomarkers such as plasma biomarker
| Condition(s) | Atrial Fibrillation, Atrial Flutter, Supraventricular Beat, Premature, Premature Supraventricular Beats, Premature Atrial Complex, Extrasystole, Atrial |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | The aim of the proposed study is to determine if individuals with excessive supraventricular ectopic activity (ESVEA) on Holter recording should be subjected to prolonged screening with Event loop recorder in order to detect previously undiagnosed Atrial fibrillation / flutter. Other biomarkers such as plasma biomarkers, high-end echocardiography and assessment of blood pressure and atrial stiffness will be studied and compared in ESVEA and control group as well as progression of atrial cardiomyopathy in ESVEA patients. |
| Who can participate | Inclusion Criteria: Patients with at least 30 supraventricular extra systole (SVES)/h or a supraventricular run of at least 20 beats on a Holter recording. Exclusion Criteria: Age \< 70 years, \>89 years Atrial fibrillation / flutter Lifelong treatment with oral anticoagulant Patients with implantable cardiac device Congestive heart failure (CHF) with Ejection fraction (EF) ≤ 30% Severe valvular heart disease |
| Ages | 70 Years to 89 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | Karolinska Institutet |
| Locations | Stockholm, Sweden |
| Start date | 2022-11-01 |
| NCT ID | NCT04593498 |
| Official listing | https://clinicaltrials.gov/study/NCT04593498 |