EXERCISE AND THE IMMUNE RESPONSE IN LUNG CANCER
This project is about the effect of a 12-week training therapy intervention in patients suffering from non-small cell and small-cell lung cancer. It has widely been accepted that exercise is preventive against certain types of cancer. Individuals following an active lifestyle have a significantly lower risk for several
| Condition(s) | Non-Small Cell Lung Cancer, Exercise Training, Immunotherapy, Small Cell Cancer Of The Lung |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | This project is about the effect of a 12-week training therapy intervention in patients suffering from non-small cell and small-cell lung cancer. It has widely been accepted that exercise is preventive against certain types of cancer. Individuals following an active lifestyle have a significantly lower risk for several chronic diseases, including cancer, as compared to sedentary ones. However, evidence is still lacking for exercise as part of routine cancer treatment. It has widely been accepted that exercise strongly impacts immune response, and might influence antitumor immune response as well. In this study, patients suffering from lung cancer undergo either a 12-week training program consisting of moderate-intensity continuous exercise (MICE), or a 12-week program with high-intensity i |
| Who can participate | Inclusion Criteria: * Patients suffering from non-small cell or small-cell lung cancer of any histologic subtype, irrespective of routine treatment regimen * ECOG 0 or 1 Exclusion Criteria: * Kachexia (BMI\<18.5) * instable bone metastases * orthopedic condition rendering the patient unable to ride a stationary bike * any medical contraindication for exercise and training * a living will against basic or advanced life support |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Lead sponsor | Medical University of Graz |
| Locations | Graz, Austria |
| Start date | 2026-04-01 |
| NCT ID | NCT07267000 |
| Official listing | https://clinicaltrials.gov/study/NCT07267000 |