Exercise Response in Humans With Obesity
This study is being done to understand how chronic inflammation affects muscle function and responses to exercise.
| Condition(s) | Obese |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | This study is being done to understand how chronic inflammation affects muscle function and responses to exercise. |
| Who can participate | Inclusion Criteria: * Obese men and women ≥ 20 and ≤ 45 years of age. Exclusion Criteria: * Diabetes or fasting plasma glucose \>126 mg/dL * Anemia (female subjects hemoglobin of \<11 g/dl and male subjects hemoglobin \<12 g/dl) * Active coronary artery disease or history of unstable macrovascular disease (unstable angina, myocardial infarction, stroke, and revascularization of coronary, peripheral or carotid artery within 3 months of recruitment) * Renal failure (serum creatinine \> 1.5mg/dl) * Chronic active liver disease defined as aspartate aminotransferase (AST)\>144 IU/L or alanine transaminase (ALT) \>165 IU/L) * Oral warfarin group medications or history of blood clotting disorders. * Smoking * Pregnancy or breastfeeding * Alcohol consumption greater than 2 glasses/day or other sub |
| Ages | 20 Years to 45 Years |
| Sex | All |
| Lead sponsor | Mayo Clinic |
| Locations | Rochester, Minnesota, United States |
| Start date | 2023-09-22 |
| NCT ID | NCT05857150 |
| Official listing | https://clinicaltrials.gov/study/NCT05857150 |