Factors Affecting Vaccine Prophylaxis Efficacy in Bone Marrow and Solid Organ Transplant R
Transplantation is one of the most challenging and complex areas of modern medicine. Besides the intrinsic complexity of the surgical and medical procedures, transplantation medicine must take into account a flawless medical management before and after transplant, especially because these patients represent a high-risk
| Condition(s) | Vaccine Prophylaxis |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | Transplantation is one of the most challenging and complex areas of modern medicine. Besides the intrinsic complexity of the surgical and medical procedures, transplantation medicine must take into account a flawless medical management before and after transplant, especially because these patients represent a high-risk group for developing infectious complications that may be vaccine-preventable, with a high mortality rate. However, there is poor evidence regarding the effectiveness of the currently available vaccines in immunocompromised patients. The aim of this study, is the development of a specific healthcare pathway for the prevention of infectious diseases for patients referred to our Hospital who are eligible for solid organ transplantation (SOT) or bone marrow transplantation (BMT |
| Who can participate | Inclusion Criteria: * Any patient eligible for SOT or BMT evaluated in our hospital * Only patients undergoing SOT or BMT will be followed-up for infections Exclusion Criteria: * Already enrolled in the study * Denied informed consent * Absolute contraindication to vaccinations |
| Sex | All |
| Lead sponsor | Fondazione IRCCS Policlinico San Matteo di Pavia |
| Locations | Pavia, Lombardy, Italy |
| Start date | 2019-09-13 |
| NCT ID | NCT07473999 |
| Official listing | https://clinicaltrials.gov/study/NCT07473999 |