Fascial Plane Blocks and Quality of Recovery in Cardiac Surgery
In this randomized trial, the investigators will test the hypothesis that combining regional analgesia techniques-which have the potential to improve the quality of postoperative recovery following median sternotomy-with PIFB will accelerate recovery. Additionally, it is anticipated that RIFB, an alternative fascial pl
| Condition(s) | Cardiovascular Surgical Procedures, Pain, Postoperative, Cardiovascular Diseases |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | In this randomized trial, the investigators will test the hypothesis that combining regional analgesia techniques-which have the potential to improve the quality of postoperative recovery following median sternotomy-with PIFB will accelerate recovery. Additionally, it is anticipated that RIFB, an alternative fascial plane block, will demonstrate non-inferior (at least as effective as) performance compared to RSB, thereby providing flexibility and ease of application in clinical practice. |
| Who can participate | Inclusion Criteria: * Patients who have provided written informed consent * Open-heart surgery performed under elective conditions via median sternotomy with cardiopulmonary bypass (on-pump) * American Society of Anesthesiologists (ASA) physical status class II or III * Aged 18-70 years Exclusion Criteria: * Off-pump surgical procedure * Emergency or repeat cardiac surgery * Known allergy to induction agents or local anesthetics * Body mass index (BMI) \>35 kg/m² * Coagulopathy * Infection at the surgical site * Left ventricular ejection fraction (LVEF) \<40% * Renal insufficiency (estimated glomerular filtration rate \<60 mL/min/1.73 m²) or hepatic insufficiency \[Presence of major systemic diseases such as acute decompensated cirrhosis characterized by bilirubin \>12 mg/dL, INR \>2.5, or |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Lead sponsor | Ordu University |
| Locations | Ordu, Altinordu, Turkey (Türkiye) |
| Start date | 2026-04-05 |
| NCT ID | NCT07557108 |
| Official listing | https://clinicaltrials.gov/study/NCT07557108 |