Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Sol
This is a pilot clinical trial determining the effect of a Methionine-reduced diet on serum levels in subjects with solid tumors. These are subjects who will receive systemic standard of care cancer therapy.
| Condition(s) | Adenocarcinoma, Basal Cell Carcinoma, Squamous Cell Carcinoma, Transitional Cell Carcinoma, Ductal Carcinoma, Osteosarcoma, Soft Tissue Sarcoma, Ewing Sarcoma, Rhabdomyosarcoma, Leiomyosarcoma, Melano |
|---|---|
| Status | Recruiting |
| Phase | EARLY_Phase 1 |
| Study type | Interventional |
| Summary | This is a pilot clinical trial determining the effect of a Methionine-reduced diet on serum levels in subjects with solid tumors. These are subjects who will receive systemic standard of care cancer therapy. |
| Who can participate | Inclusion Criteria: * Age: Subjects must be 18 years of age or older. * Diagnosis: Has a diagnosis of metastatic, recurrent, or unresectable solid tumors. * Life Expectancy: Subjects must have an expected life expectancy of at least 3 months. * Performance Status: Subjects must have an ECOG performance status of 0-2. * Organ Function: Subjects must have adequate organ function, as determined by the investigator through review of standard labs. * Pregnancy and Contraception: Women of childbearing potential (WOCBP) must have a negative pregnancy test within 7 days prior to study enrollment and must agree to use adequate contraception throughout the study period and for 30 days after the last dose of study treatment. Female patients who are considered not to be of childbearing potential must |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | University of California, Irvine |
| Locations | Orange, California, United States |
| Start date | 2026-05-01 |
| NCT ID | NCT07628634 |
| Official listing | https://clinicaltrials.gov/study/NCT07628634 |