Forced Oscillometry in Infants With Bronchopulmonary Dysplasia
The purpose of this study is to use forced oscillometry technique (FOT) to measure pulmonary mechanics and function in in term infants and premature infants with bronchopulmonary dysplasia (BPD)
| Condition(s) | Infant, Premature, Diseases, Bronchopulmonary Dysplasia, Respiratory Distress Syndrome |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | The purpose of this study is to use forced oscillometry technique (FOT) to measure pulmonary mechanics and function in in term infants and premature infants with bronchopulmonary dysplasia (BPD) |
| Who can participate | Inclusion Criteria: Preterm Cohort: * Premature infants with BPD who are in room air based on the (per NICHD definition) * Premature infants with BPD who are receiving low flow O2 support and able to maintain normal spO2 in Room air for brief period ( up to 3 minutes) Term Cohort without pulmonary disease * Infants \>36 weeks gestational age without pulmonary disease * Infants \< 4 weeks of age Outpatient Cohort: * Former preterm infants \< 32 weeks at birth * Those with BPD based on NIH 2001 definition * Seen prior to 2 years of age Exclusion Criteria: * Infants with BPD requiring invasive or non-invasive positive pressure ventilation * Infants with BPD who have associated genetic diagnosis or major congenital anomalies. |
| Sex | All |
| Lead sponsor | Winston Manimtim |
| Locations | Kansas City, Missouri, United States |
| Start date | 2020-02-06 |
| NCT ID | NCT04270045 |
| Official listing | https://clinicaltrials.gov/study/NCT04270045 |