Fractional CO2 Laser-assisted Delivery of Hyaluronic Acid, Ascorbic Acid and Sodium DNA Fo
Evaluate the effectiveness of topical hyaluronic acid, ascorbic acid, and sodium DNA following ablative fractional laser treatment in objectively reversing facial skin alterations induced by photoaging.
| Condition(s) | Skin Quality Improvement, Photo-aged Skin, Drug Delivery Systems |
|---|---|
| Status | Recruiting |
| Phase | Phase 4 |
| Study type | Interventional |
| Summary | Evaluate the effectiveness of topical hyaluronic acid, ascorbic acid, and sodium DNA following ablative fractional laser treatment in objectively reversing facial skin alterations induced by photoaging. |
| Who can participate | Inclusion Criteria: * Male and female subjects, over 30 years of age, with moderate skin changes associated with elasticity, wrinkles, roughness, pigmentation, erythema, and pore size; with at least 12 points on the SASSQ scale. Fitzpatrick skin type I-III. Participants who agree to take part in the protocol Exclusion Criteria: * Fitzpatrick skin type IV-VI. Local infections or inflammatory disorders.. Neoplasms suspected of being malignant. Allergy to hyaluronic acid, ascorbic acid, and sodium DNA. Hypersensitivity to fractional CO2 laser. Pregnancy or breastfeeding. Local or systemic adverse reaction |
| Ages | 30 Years |
| Sex | All |
| Lead sponsor | Instituto de Oftalmología Fundación Conde de Valenciana |
| Locations | Mexico City, Mexico City, Mexico |
| Start date | 2025-11-07 |
| NCT ID | NCT07376148 |
| Official listing | https://clinicaltrials.gov/study/NCT07376148 |